Skin tissue regeneration for burn injury

The skin is the largest organ of the body, which meets the environment most directly. Thus, the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a serious interaction between cell types, cytokines, mediators, the neurovascular system, and matrix remodeling. Tissue regeneration technology remarkably enhances skin repair via re-epidermalization, epidermal-stromal cell interactions, angiogenesis, and inhabitation of hypertrophic scars and keloids. The success rates of skin healing for burn injuries have significantly increased with the use of various skin substitutes. In this review, we discuss skin replacement with cells, growth factors, scaffolds, or cell-seeded scaffolds for skin tissue reconstruction and also compare the high efficacy and cost-effectiveness of each therapy. We describe the essentials, achievements, and challenges of cell-based therapy in reducing scar formation and improving burn injury treatment.

The wound healing under different treatments and burn-induced

An active ingredient isolated from Ganoderma lucidum promotes burn wound healing via TRPV1/SMAD signaling. - Abstract - Europe PMC

Burn wound surface after 3 days (A) and wound area after removal of

Transplantation of human induced pluripotent stem cell derived

Burn wound healing: present concepts, treatment strategies and future directions.

/upload//thumbnails/jwmr-2022-02313f4.

Skin-like wound dressings with on-demand administration based on in situ peptide self-assembly for skin regeneration - Journal of Materials Chemistry B (RSC Publishing) DOI:10.1039/D2TB00348A

Spray-on skin' helps young man regenerate skin tissue - UCHealth Today

Skin tissue engineering - stem cell and wound healing - Sergio Mazzei

Recent Advancements in Applications of Chitosan-based Biomaterials for Skin Tissue Engineering

Cells, Free Full-Text

Skin tissue engineering advances in severe burns: review and

Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies

Cell therapies for skin regeneration: an overview of 40 years of