Schematic depiction of the distribution of the PV autoantigens Dsg1

Download scientific diagram | | Schematic depiction of the distribution of the PV autoantigens Dsg1 (green) and Dsg3 (red) and the composition of desmosome along different epidermal layers in normal epidermis (left) and PV-affected epidermis (right). *Significant difference to the value which is indicated that it is compared to. from publication: Dsg1 and Dsg3 Composition of Desmosomes Across Human Epidermis and Alterations in Pemphigus Vulgaris Patient Skin | Desmosomes are important epidermal adhesion units and signalling hubs, which play an important role in pemphigus pathogenesis. Different expression patterns of the pemphigus autoantigens desmoglein (Dsg)1 and Dsg3 across different epidermal layers have been demonstrated. | Desmosomes, Pemphigus and Epidermis | ResearchGate, the professional network for scientists.

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Daniela KUGELMANN, Ludwig-Maximilians-University of Munich, München, LMU, Faculty of Medicine

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